CURRICULUM VITAE
Laurie A. Keefer, Ph.D.

I. Personal Data

Current Position:

Assistant Professor of Medicine, Psychiatry & Behavioral Sciences
Clinical Health Psychologist, Division of Gastroenterology
Director, Center for Psychosocial Research in IBD
Northwestern University, Feinberg School of Medicine

Academic Office:
Northwestern University Feinberg School of Medicine
Division of Gastroenterology
676 N. St. Clair, Suite 1400
Chicago, IL 60611
p.312-695-0076
f. 312-695-3999
email: laurie.keefer@northwestern.edu

Clinical Office:
Northwestern Medical Faculty Foundation
Division of Gastroenterology
675 N. St. Clair, Galter 17-250
312-695-5620

Websites:
www.ibdpsych.org
www.northwesternmotility.com

II. Education (reverse chronology)

2003 Post-doctoral Fellowship (Health Psychology)
Section of Gastroenterology & Nutrition
Rush University Medical Center Chicago, IL

2002 Pre-doctoral Residency (Health Psychology)
Rush University Medical Center Chicago, IL

2000-2003 Doctor of Philosophy (Clinical Psychology)
University of Albany—State University of New York Albany, NY
Doctoral Dissertation: The effectiveness of a cognitive-behavioral support group on hot flashes and related symptoms of perimenopause
Chair: Edward B. Blanchard, PhD

1998-2000 Masters of Arts (Clinical Psychology)
University of Albany—State University of New York Albany, NY
Masters Thesis: The treatment of irritable bowel syndrome with relaxation response meditation
Chair: Edward B. Blanchard, PhD

1994-1997 Bachelor of Arts (Psychology/Women’s Studies)
The Pennsylvania State University University Park, PA


III. Board Certification and Licensure Medical Licensure:
Illinois (071-006737), Clinical Psychology

IV. Honors and Awards
Initiatives for Women Presidential Award, University at Albany, 2001
Scholarship Award for Masters Thesis, Association for Applied Psychophysiology and Biofeedback, 2000
Phi Beta Kappa, 1997

V. Military Service: n/a

VI. Faculty Appointments
1/2006-present
Assistant Professor of Medicine and Psychiatry
Northwestern University, Feinberg School of Medicine Chicago, IL

2004-2005
Assistant Professor of Medicine and Behavioral Sciences
Rush University Medical Center Chicago, IL

2003-2004
Instructor Rush University Medical Center Chicago, IL

VII. Hospital Staff and Administrative Appointments
2007-present
Member, General Faculty Council, Research Affairs Committee
Northwestern University, Chicago, IL

2005 Member, Colloquium Committee, Department of Behavioral Sciences
Rush University Medical Center , Chicago, IL
VIII. Summary of Teaching Experience
2007-present
Dissertation Committees Member, Dissertation Committee—Clinical Psychology Northwestern Feinberg School of Medicine “The Effects of a Behavioral Weight Loss Intervention on Barriers to Physical Activity in Obese African-American Women” Allison Thompson, MA; Defended July 26, 2007

Member, Dissertation Committee—Clinical Psychology Chicago Professional School of Psychology, Chicago, IL “Perceived Stigma in Inflammatory Bowel Disease: An Exploratory Study ” Tiffany Havlicek, MA, MS; Anticipated Defense Date June, 2008

2006- present Northwestern University
Weekly clinical supervision of psychosomatic medicine fellow; weekly supervision of health psychology fellow and psychotherapy practicum student; Lectures to medical students on stress and health; Lectures to clinical psychology graduate students on CBT for gastrointestinal diseases

2004-2005 Rush University
Weekly clinical supervision of 2 Health Psychology post-doctoral fellows—liver transplant; Weekly clinical supervision of a health psychology resident in obesity; Primary mentorship of masters thesis research projects for 2 graduate students in the MS of clinical research program at Rush University; Supervision of gastroenterology fellow’s research projects; Monthly responsibility for a 2 hour seminar for 3rd year medical students. Seminar entitled “Clinical Approaches to Obesity”; 2-4 lectures/year at Health Psychology Seminar on psychosocial & professional issues relevant to gastroenterology & hepatology

2002 University at Albany, State University of New York
Instructor, Child Development Full responsibility for large (300+) undergraduate course in child development

2001 Instructor, Research Seminar in Behavioral Medicine Full responsibility for a small (12) undergraduate course that focused on research skills and research design relevant to behavioral medicine. Supervised research/writing projects and senior theses for students receiving writing-intensive credit.

IX. Professional and Scientific Activity
Current Memberships
American Gastroenterological Association
American Psychosomatic Society
American Psychological Association ( Health Psychology Psychology of Women)
Association for the Advancement of Cognitive-Behavioral Therapy
|Crohn’s and Colitis Foundation of America
Functional Brain Gut Research Group

Activities
Editorial Board: Biological Research for Nursing (2007 to present)
Ad Hoc Reviewer: American Journal of Gastroenterology, Behavior Research and Therapy, Biological Research for Nursing, BMC Psychiatry, Inflammatory Bowel Disease Monitor, Journal of Cognitive Psychotherapy, Journal of Consulting and Clinical Psychology, Psychological Bulletin

X. Research Grants and Contracts
Funded
NIH-NCCAM, R21AT003204-01A2, “The role of gut-directed hypnotherapy on relapse prevention in Ulcerative Colitis.” $425,000 direct costs, Principal Investigator

NIH-NIDDK, R01 DK077738-01 “The efficacy of minimal contact cognitive-behavioral therapy for irritable bowel syndrome.” $7 million total direct costs; Co-Principal Investigator (Northwestern Site)

Completed Projects
Rush University Committee on Research (UCR) (2005-2007). “The relations between sleep and intestinal inflammation” $20,000, Principal Investigator

NIMH, R01, 5R01MH067057-03 (2003-2008). “Classifying Psychiatric, Medical, and Primary Insomnias,” $2.2million, Investigator

NIH-NIDDK, R24, DK067674 (2006-2007). Gastrointestinal Biopsychosocial Research Program Seed Grant Award. “Stigma in the irritable bowel syndrome: development of a condition-specific measure and relationship to quality of life,” $35,000, Co-Investigator
XI. Scholarly Productivity
Refereed Journals (in chronological order)
1. Keefer L, Blanchard EB. The effects of relaxation response meditation on irritable bowel syndrome: Results of a controlled treatment trial. Behavior Research and Therapy 2001; 39: 801-811.

2. Blanchard EB, Keefer L, Galovski TE, Turner S, Taylor A. Gender differences in the irritable bowel syndrome. Psychosomatic Research 2001; 50: 271-275.

3. Keefer L, Blanchard EB. A one year follow-up of the effects of relaxation response meditation on irritable bowel syndrome. Behaviour Research and Therapy 2002; 40: 541-546.

4. Blanchard EB, Keefer L, Payne A, Turner S, Galovski TE. Early abuse, psychiatric diagnoses and irritable bowel syndrome. Behaviour Research and Therapy, 2002; 40: 289-298.

5. Blanchard EB., Hickling EJ, Veazey CH, Buckley TC, Freidenberg, BM, Walsh JD, Keefer L. Treatment-related changes in cardiovascular reactivity to trauma cues in motor vehicle accident- related PTSD. Behavior Therapy 2002; 33: 417-426.

6. Sykes, MA, Blanchard EB, Lackner JM, Keefer L. Krasner S. Psychopathology in irritable bowel syndrome: Support for a psychosomatic model. Journal of Behavioral Medicine, 2003; 26: 361-372.

7. Blanchard EB, Keefer L, Galovski TE, Lackner JM, Krasner S, Norman S, Sykes M. The role of childhood abuse in Axis I and Axis II psychiatric disorders and medical disorders of unknown origin
among irritable bowel syndrome patients. Journal of Psychosomatic Research, 2004; 56: 431-6.

8. Keefer L, Blanchard EB. A behavioral treatment program for menopausal hot flashes: Results of a pilot study. Applied Psychophysiology and Biofeedback 2005; 30: 21-30.

9. Keefer L, Blanchard EB. Hot Flash, Hot Topic: Conceptualizing menopausal symptoms from a cognitive-behavioral perspective. Applied Psychophysiology and Biofeedback 2005; 30: 75-83.

10. Keefer L, Sanders K, Sykes MA, Blanchard EB, Lackner JM, Krasner S. Towards a better understanding of anxiety in irritable bowel syndrome: A preliminary look at worry and intolerance of uncertainty. Journal of Cognitive Psychotherapy 2005; 19: 53-62.

11. Blanchard EB, Lackner JM, Gusmano R, Gudleski GD, Sanders K, Keefer L, Krasner S. Prediction of outcome among patients with irritable bowel syndrome treated with group cognitive therapy. Behaviour Research and Therapy 2006; 44: 317-37.

12. Keefer, L, Stepanski, EJ, Ranjbaran, Z, Benson, LM, Keshavarzian, A. An initial report of sleep disturbance in inactive inflammatory bowel disease. Journal of Clinical Sleep Medicine, 2006, 2, 409-16.

13. Ranjbaran Z., Keefer L., Farhadi, A, Stepanski, EJ, Sedghi, S, Keshavarzian, A. Impact of sleep disturbances in inflammatory bowel disease. Journal of Gastroenterology and Hepatology, 2007; 11: 1748-53.

14. Blanchard EB, Lackner JM, Sanders K, Krasner, S, Keefer L, Payne A, Gudleski GD, Katz L, Rowell D, Sykes M, Kuhn E, Gusmano R, Carosella AM, Firth R, Dulgar-Tulloch L. A controlled evaluation of group cognitive therapy in the treatment of irritable bowel syndrome. Behaviour Research and Therapy, 2007; 45: 633-8.

15. Ranjbaran Z., Keefer L, Stepanski EJ, Farhadi A., Keshavarzian A. The relevance of sleep abnormalities to chronic inflammatory conditions. Inflammation Research, 2007, 56, 51-7.

16. Keefer L., Keshavarzian A. Feasibility and acceptability of gut-directed hypnotherapy on Inflammatory Bowel Disease: A brief communication. International Journal of Clinical & Experimental Hypnosis, 2007; 55, 457-66.

17. Jones MP, Havlicek T, Bratten J., Keefer L. Quality of life in patients with inflammatory bowel disease and irritable bowel syndrome differs between subjects recruited from clinic or the internet. American Journal of Gastroenterology, in press.

18. Keefer, L., Sayuk, G, Bratten, J., Rahimi, R, and Jones, MP. Multicenter Study of Gastroenterologists' Ability to Identify Anxiety and Depression in a New Patient Encounter and its Impact on Diagnosis. Journal of Clinical Gastroenterology, in press.
Published Abstracts
1. Keefer L. The effect of a cognitive-behavioral group treatment on perimenopausal hot flashes and related symptoms. (Doctoral dissertation, University at Albany, State University of New York, 2003). Dissertation Abstracts International, 2003; 64: 2923.

2. Keefer L, Blanchard EB. Relaxation response meditation: A treatment for irritable bowel syndrome. Applied Psychophysiology and Biofeedback Proceedings, 2000, 50-51.

3. Lackner, JM, Blanchard EB, Krasner SS, Firth RS, Gudleski GD, Sanders K, Keefer, L., Katz, LA, Carosella A, Payne A. Are psychological treatments for IBS effective for the full spectrum of GI symptoms for which patients seek treatment? Results of a multi-site randomized controlled study. Proceedings of Digestive Diseases Week, May, 2005

4. Ranjbaran, Z., Keefer, L., Sedghi, S., Keshavarzian, A. Can disrupted sleep predispose flare-up in inflammatory bowel disease (IBD)? The American Journal of Gastroenterology, 2005; 100, S287.

5. Keefer, L, Stepanski, EJ, Benson, L, Ranjbaran, Z, Keshavarzian, A. Sleep Disruption in Patients with Inflammatory Bowel Disease (IBD). Sleep. In press.

6. Jones, MP, Havlicek, TN, Bratten, J, Keefer, L. Anxiety, stress, vital exhaustion and cynical hostility in irritable bowel syndrome. Psychosomatic Medicine; 2006; 68: A98.

7. Havlicek, T, Jones, MP, Williams, M, Rahimi, R., Keefer, L. Gastroenterologist ratings of patient anxiety: Perception or attribution? Psychosomatic Medicine; 2006; 68: A99.

8. Rahimi, R., Keefer, L., Sedghi, S., Mutlu, E., Keshavarzian, A. The impact of negative affectivity and conscientiousness on quality of life and symptom severity in patients with inflammatory bowel disease. Gastroenterology; 2006; 130: A137.

9. Keefer, L., Keshavarzian, A., Ranjbaran, Z., Benson, L., Stepanski, EJ. The impact of sleep disruption on quality of life in IBD and IBS. Gastroenterology; 2006; 130: A161.

10. Swanson, G., Keefer, L., Kwasny, M., Sedghi, S., Keshavarzian, A. The effect of current alcohol consumption in inactive inflammatory bowel disease. Gastroenterology; 2006; 130: A623.

11. Havlicek T, Bratten J, Klein M, Keefer L, Jones MP. Quality of life in Inflammatory Bowel Disease and Irritable Bowel Syndrome: a pilot comparison of clinic and online respondents. Am J Gastroenterol 2006; 101:S414.

12. Jones MP, Bratten J, Keefer L. Predictors of quality of life in functional dyspepsia. Am J Gastroenterol 2006; 101:S477.

13. Havlicek T, Bratten J., Keefer L., Jones MP. Subjective experiences of irritable bowel syndrome patients: An exploratory study of the social stigma of IBS. Gastroenterology; 2007; 134:A521.

14. Jones MP, Havlicek T, Keefer L, Bratten J, Norton N, Crowell MD, Levy R, Palsson O. The perceived stigma scale in IBS: A preliminary report on development and validation. Gastroenterology, 2007; 134:A521.

15. Keefer L., Sayuk GS, Williams M, Rahimi R, Bratten J, Jones MP. Determinants of patient satisfaction at the initial patient encounter. Gastroenterology; 2007; 134:A645.
Presentations
1. Galovski TE, Keefer L, Blanchard EB, Turner SM. The differential impact of psychopathology versus a history of sexual abuse in an irritable bowel syndrome population. Presented November, 2000 at Annual Meeting of Association for the Advancement of Behavior Therapy.

2. Keefer L, Blanchard EB. A controlled study of the effectiveness of meditation as a treatment for irritable bowel syndrome. Presented November, 2000 at Annual Meeting of Association for the Advancement of Behavior Therapy.

3. Keefer L, Galovski TE, Blanchard EB. Irritable bowel syndrome and psychological distress: An analysis of gender differences. Presented November, 2000 at Annual Meeting of Association for the Advancement of Behavior Therapy.

4. Kuhn E, Veazey C, Keefer L, Blanchard EB, Hickling EJ. Changes in the psychosocial functioning of MVA survivors depending on PTSD diagnostic status. Presented November, 2000 at Annual Meeting of Association for the Advancement of Behavior Therapy.

5. Kuhn E, Keefer L, Sykes MA, Blanchard EB. PTSD symptoms in MVA survivors: Predictors of psychosocial functioning. Presented November, 2000 at the Annual Meeting of Association for the Advancement of Behavior Therapy.

6. Keefer L, Blanchard EB, Payne A, Turner, SM, Galovski TE. Can the high incidence of psychiatric disorders in IBS patients be explained by a history of abuse? Presented November, 2001 at Annual Meeting of Association for the Advancement of Behavior Therapy.

7. Keefer L, Kuhn E., Sykes MA, Sanders K, Blanchard EB, Lackner JM. Predicting health care utilization in a sample of IBS patients. Presented November, 2001 at Annual Meeting of Association for the Advancement of Behavior Therapy.

8. Keefer L, Sykes MA, Kuhn E, Sanders K, Blanchard EB, Lackner JM. Functional vs. organic pain symptoms and psychological distress in an IBS population. Presented November, 2001 at Annual Meeting of Association for the Advancement of Behavior Therapy.

9. Keefer L, Small ER, Walsh JD, Blanchard EB. Femininity, gender role conflict and IBS symptom reporting. Presented November, 2001 at Annual Meeting of Association for the Advancement of Behavior Therapy.

10. Sanders K, Kuhn E, Keefer L, Sykes M, Blanchard EB, Lackner JM. Pain and depression as predictors of quality of life in irritable bowel syndrome. Presented November, 2001 at Annual Meeting of Association for the Advancement of Behavior Therapy.

11. Galovski TE, Keefer L, Blanchard EB. Psychological distress and gender differences in an irritable bowel syndrome population. Presented March, 2001 at the Society of Behavioral Medicine Annual Symposium.

12. Rowell D., Keefer L., Sykes M., Gusmano R., Sanders K., Blanchard EB., Lackner JM. How does chronicity of gastrointestinal distress relate to symptom severity and psychopathology? Presented November, 2002 at Annual Meeting of Association for the Advancement of Behavior Therapy.

13. Gusmano R, Tatrow K, Rowell D, Keefer L, Donovan K, Blanchard EB. Perceived stress and chronic headache: A prospective study. Presented November, 2002 at Annual Meeting of Association for the Advancement of Behavior Therapy.

14. Keefer L, Lazarovits N, Blanchard EB. Hot flashes and cognitive-behavioral support groups: Is there an alternative to hormone replacement therapy? Presented November, 2002 at Annual Meeting of Association for the Advancement of Behavior Therapy.

15. Sykes MA, Keefer L, Sanders K, Blanchard EB. Child abuse and its relationship to gastrointestinal symptoms in irritable bowel syndrome. Presented November, 2002 at Annual Meeting of Association for the Advancement of Behavior Therapy

16. Sykes MA, Sanders K, Blanchard EB, Keefer L, Lackner JM. Gastrointestinal symptom severity and psychological distress as predictors of quality of life in an IBS sample. Presented November, 2002 at Annual Meeting of Association for the Advancement of Behavior Therapy.

17. Rahimi, R., Keefer, L., Sedghi, S., Mutlu, E., Keshavarzian, A. The impact of negative affectivity and conscientiousness on quality of life and symptom severity in patients with inflammatory bowel disease. Oral Presentation: AGA Institute Research Forum, IBD Assessments and Outcomes, May 2006, Digestive Diseases Week.

18. Havlicek T, Bratten J, Keefer L, Jones MP. Subjective Experiences of Irritable Bowel Syndrome (IBS) Patients: An Exploratory Study of the Social Stigma of IBS. Poster presented at Illinois Psychological Association Annual Meeting, Oct 2006, Chicago IL.

19.. Keefer L., Sayuk G, Williams M, Rahimi R, Bratten J., Havlicek T, Jones, MP. Gastroenterologist perceptions of patient anxiety and depression: Is poor perception misattribution? Oral Presentation: AGA Institute Research Forum, Functional Gastrointestinal Disorders: Symptoms, Diagnosis and Validation, May 2007, Digestive Diseases Week

Invited Lectures, Visiting Professorships
June, 1999 Departmental Colloquium, Department of Psychology, University at Albany, Albany, NY “Meditation as a treatment for Irritable Bowel Syndrome”

May, 1999 Training Workshop, Center for Stress and Anxiety Disorders, Albany, NY “Empirically supported treatments for irritable bowel syndrome and chronic headache”

April, 2002 Departmental Colloquium, Department of Psychology, University at Albany, Albany, NY “Non-drug treatments for symptoms of perimenopause”

January, 2002 Invited address, Albany Gynecology Associates, Albany, NY “Alternative approaches to the management of hot flashes” October, 2002 Sleep Medicine Grand Rounds, Rush University Medical Center, Chicago, IL “Sleep during perimenopause”

December, 2002 Sleep Medicine Grand Rounds, Rush University Medical Center, Chicago, IL “Sleep and GI function” June, 2003 Primary Care Grand Rounds, Rush University Medical Center, Chicago, IL “Physician Approach to Unexplained Physical Symptoms”


November, 2003 Gastroenterology/Hepatology Grand Rounds, Rush University Medical Center, Chicago, IL “Psychological Approaches to Irritable Bowel Syndrome: Care for the Refractory Patient”

April, 2004 Gastroenterology/Hepatology Grand Rounds, Rush University Medical Center, Chicago, IL “Stress and Inflammation in IBD”

October, 2005 Continuing Medical Education Program, Chicago, IL “Managing the Challenges of Pelvic Floor Symptoms: Practical Approaches to Pain, Incontinence and Prolapse: Behavioral Approaches to Patients with Pelvic and Abdominal Problems

November, 2005 Gastroenterology Grand Rounds, Northwestern University, Chicago, IL “Psychosocial Assessment and Treatment of Functional Bowel Disorders”

January, 2007 Wellness Institute Grand Rounds, Chicago, IL “ Lifestyle approaches to functional bowel disorders”

May, 2007 Digestive Diseases Week, Meet the Professor Luncheon, Washington DC “Psychotherapy in the Treatment of Irritable Bowel Syndrome”

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